The role of adolescent lifestyle habits in biological aging: A prospective twin study.

ABSTRACT:

Background

Adolescence is a stage of fast growth and development. Exposures during puberty can have long-term effects on health in later life. This study aims to investigate the role of adolescent lifestyle in biological aging.

Methods

The study participants originated from the longitudinal FinnTwin12 study (n = 5114). Adolescent lifestyle-related factors, including body mass index (BMI), leisure-time physical activity, smoking, and alcohol use, were based on self-reports and measured at ages 12, 14, and 17 years. For a subsample, blood-based DNA methylation (DNAm) was used to assess biological aging with six epigenetic aging measures in young adulthood (21-25 years, n = 824). A latent class analysis was conducted to identify patterns of lifestyle behaviors in adolescence, a

SUBMITTER: Kankaanpaa A 

PROVIDER: S-EPMC9642990 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature