Regional differences in utilization of 17α-hydroxyprogesterone caproate (17-OHP).

ABSTRACT:

Objectives

To describe regional differences in utilization of 17α-hydroxyprogesterone caproate (17-OHP).

Methods

Retrospective cohort study of a large, US commercial managed care plan claims database with pharmacy coverage from 2008 to 2018. Singleton pregnancies with at least one prior spontaneous preterm birth (sPTB) were included. Regional and state-based differences in 17-OHP use were compared. Data were analyzed using t-tests and Fisher's exact tests.

Results

Of the 4,514 individuals with an indication for 17-OHP, 580 (12.8%) were prescribed 17-OHP. Regional and state-based differences in 17-OHP utilization were identified; Northeast 15.7%, Midwest 13.7%, South 12.0%, and West 10.4% (p=0.003).

Conclusions

While significant regional differences in 17-OHP ut

SUBMITTER: Hart JM 

PROVIDER: S-EPMC9643047 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature