Towards a knowledge graph for pre-/probiotics and microbiota-gut-brain axis diseases.

ABSTRACT: Scientific publications present biological relationships but are structured for human reading, making it difficult to use this resource for semantic integration and querying. Existing databases, on the other hand, are well structured for automated analysis, but do not contain comprehensive biological knowledge. We devised an approach for constructing comprehensive knowledge graphs from these two types of resources and applied it to investigate relationships between pre-/probiotics and microbiota-gut-brain axis diseases. To this end, we created (i) a knowledge base, dubbed ppstatement, containing manually curated detailed annotations, and (ii) a knowledge base, called ppconcept, containing automatically annotated concepts. The resulting Pre-/Probiotics Knowledge Graph (PPKG) combines these

SUBMITTER: Liu T 

PROVIDER: S-EPMC9643397 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature