Prognostic model for the exemption of adjuvant chemotherapy in stage IIIC endometrial cancer patients.

ABSTRACT:

Background

This study aimed to develop a nomogram to predict the survival for stage IIIC endometrial cancer (EC) patients with adjuvant radiotherapy (ART) alone and personalize recommendations for the following adjuvant chemotherapy (ACT).

Methods

In total, 746 stage IIIC EC patients with ART alone were selected from the Surveillance, Epidemiology, and End Results (SEER) registry. Cox regression analysis was performed to identify independent risk factors. A nomogram was developed accordingly, and the area under the receiver operating characteristic curve (AUC) and C-index were implemented to assess the predictive power. The patients were divided into different risk strata based on the total points derived from the nomogram, and survival probability was compared between each

SUBMITTER: Yang XL 

PROVIDER: S-EPMC9643711 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature