Updates in combined approaches of radiotherapy and immune checkpoint inhibitors for the treatment of breast cancer.

ABSTRACT: Breast cancer is the most prevalent non-skin cancer diagnosed in females and developing novel therapeutic strategies to improve patient outcomes is crucial. The immune system plays an integral role in the body's response to breast cancer and modulating this immune response through immunotherapy is a promising therapeutic option. Although immune checkpoint inhibitors were recently approved for the treatment of breast cancer patients, not all patients respond to immune checkpoint inhibitors as a monotherapy, highlighting the need to better understand the biology underlying patient response. Additionally, as radiotherapy is a critical component of breast cancer treatment, understanding the interplay of radiation and immune checkpoint inhibitors will be vital as recent studies suggest that com

SUBMITTER: Jungles KM 

PROVIDER: S-EPMC9643771 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature