Humoral response to SARS-CoV-2 vaccination in haemodialysis patients and a matched cohort.

ABSTRACT:

Objectives

SARS-CoV-2 vaccination is a crucial intervention for infection control; however, the immune response to vaccination in dialysis patients has been reported to be moderate compared with healthy adults. There are few studies available on humoral response in immunised dialysis patients compared with well-matched control group, we conducted a prospective cohort study measuring SARS-CoV-2 antibody titres in Fukushima Prefecture, Japan since September 2021.

Participants

We compared the titres of both anti-SARS-CoV-2 S1 IgG and neutralising antibodies of 65 haemodialysis patients (dialysis group) with 500 residents in Soma, Fukushima (control group).

Methods

Coarsened exact matching was used to balance sex, age and days from the second dose between dialysis and con

SUBMITTER: Zhao T 

PROVIDER: S-EPMC9644083 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature