Association of Patient and Site-of-Care Characteristics With Reproductive Carrier Screening Timing in a Large Integrated Health System.

ABSTRACT:

Importance

Reproductive genetic carrier screening can be performed prior to or during pregnancy to assess a reproductive couple's risk of having a child with a recessively inherited disorder. Although professional societies endorse preconception screening as preferable to prenatal screening to allow for greater reproductive choice, implementation of preconception screening is challenging.

Objective

To determine how carrier screening timing varies by multilevel factors associated with health care delivery including patient, clinician, and location across a large integrated health care system.

Design, setting, and participants

This cross-sectional study used a mixed-methods approach including (1) quantitative analysis of multilevel factors associated with the timing of

SUBMITTER: Hull LE 

PROVIDER: S-EPMC9644263 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature