Dietary and/or physical activity interventions in women with overweight or obesity prior to fertility treatment: protocol for a systematic review and individual participant data meta-analysis.

ABSTRACT:

Introduction

Dietary and/or physical activity interventions are often recommended for women with overweight or obesity as the first step prior to fertility treatment. However, randomised controlled trials (RCTs) so far have shown inconsistent results. Therefore, we propose this individual participant data meta-analysis (IPDMA) to evaluate the effectiveness and safety of dietary and/or physical activity interventions in women with infertility and overweight or obesity on reproductive, maternal and perinatal outcomes and to explore if there are subgroup(s) of women who benefit from each specific intervention or their combination (treatment-covariate interactions).

Methods and analysis

We will include RCTs with dietary and/or physical activity interventions as core intervention

SUBMITTER: Evans-Hoeker E 

PROVIDER: S-EPMC9644352 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature