Dataset Information

Fatal overdose from injection of human growth hormone; a case report and review of the literature.

ABSTRACT:

Background

Human growth hormone (HGH) is a categorized as a performance-enhancing substance. HGH has been abused by athletes for doping purposes.

Case presentation

We present a first lethal case of HGH acute toxicity. A young-agitated-athlete with a history of somatropin for the past 2-year, who had hallucinations referred to the emergency department reporting to have abused of 300 mg subcutaneous injections of HGH. He was tachycardic with mild hypertension. Lab data revealed hypernatremia (157 mEq/L), hyperkalemia (5.3 mEq/L), high LDH (1448 U/L), and CPK (2620 U/L), in favor of rhabdomyolysis. Routine drug screening tests were negative for all substances. He was intubated due to low O₂ saturation and progressive loss of consciousness. After several episodes of hyperthermia, hypertension, and possibly pulmonary embolism, he died subsequent to somatropin overdose.

Conclusions

Complications of HGH misuse can be life-threatening and athletes should be warned of its deleterious effects.

SUBMITTER: Erfanifar A

PROVIDER: S-EPMC9644502 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Publications

Fatal overdose from injection of human growth hormone; a case report and review of the literature.

Erfanifar Azam A Mahjani Mahsa M Gohari Sepehr S Hassanian-Moghaddam Hossein H

BMC endocrine disorders 20221108 1

<h4>Background</h4>Human growth hormone (HGH) is a categorized as a performance-enhancing substance. HGH has been abused by athletes for doping purposes.<h4>Case presentation</h4>We present a first lethal case of HGH acute toxicity. A young-agitated-athlete with a history of somatropin for the past 2-year, who had hallucinations referred to the emergency department reporting to have abused of 300 mg subcutaneous injections of HGH. He was tachycardic with mild hypertension. Lab data revealed hype ...[more]

PMID: 36348360

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Dataset Information

Fatal overdose from injection of human growth hormone; a case report and review of the literature.

Background

Case presentation

Conclusions

Publications

Fatal overdose from injection of human growth hormone; a case report and review of the literature.

Similar Datasets

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