Risk factors for natural menopause before the age of 45: evidence from two British population-based birth cohort studies.

ABSTRACT:

Background

Menopause that occurs before the age of 45 and is not medically induced (referred to here as 'early natural menopause') affects around one in 10 women and has serious health consequences. These consequences include increased risk of all-cause mortality, cardiovascular disease, osteoporosis, and type 2 diabetes.

Methods

We investigate risk factors for the onset of natural menopause before the age of 45 in two population-based prospective cohort studies in Britain: the 1958 cohort following 8959 women and the 1970 cohort following 8655 women. These studies follow women from birth to adulthood, and we use harmonized data on birth and early life characteristics, reproductive health, health behaviour, and socioeconomic characteristics for 6805 women who were pre-menopa

SUBMITTER: Peycheva D 

PROVIDER: S-EPMC9644638 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature