Test-Retest Reliability of an Adaptive Thermal Pain Calibration Procedure in Healthy Volunteers.

ABSTRACT: Quantitative sensory testing (QST) allows researchers to evaluate associations between noxious stimuli and acute pain in clinical populations and healthy participants. Despite its widespread use, our understanding of QST's reliability is limited, as reliability studies have used small samples and restricted time windows. We examined the reliability of pain ratings in response to noxious thermal stimulation in 171 healthy volunteers (n = 99 female, n = 72 male) who completed QST on multiple visits ranging from 1 day to 952 days between visits. On each visit, participants underwent an adaptive pain calibration in which they experienced 24 heat trials and rated pain intensity after stimulus offset on a 0 to 10 Visual Analog Scale. We used linear regression to determine pain threshold, pain to

SUBMITTER: Amir C 

PROVIDER: S-EPMC9644806 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature