Clinical and cost effectiveness of single stage compared with two stage revision for hip prosthetic joint infection (INFORM): pragmatic, parallel group, open label, randomised controlled trial.

ABSTRACT:

Objectives

To determine whether patient reported outcomes improve after single stage versus two stage revision surgery for prosthetic joint infection of the hip, and to determine the cost effectiveness of these procedures.

Design

Pragmatic, parallel group, open label, randomised controlled trial.

Setting

High volume tertiary referral centres or orthopaedic units in the UK (n=12) and in Sweden (n=3), recruiting from 1 March 2015 to 19 December 2018.

Participants

140 adults (aged ≥18 years) with a prosthetic joint infection of the hip who required revision (65 randomly assigned to single stage and 75 to two stage revision).

Interventions

A computer generated 1:1 randomisation list stratified by hospital was used to allocate participants with prosthetic joi

SUBMITTER: Blom AW 

PROVIDER: S-EPMC9645409 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature