Laboratory signatures differentiate the tolerance to hypothermic circulatory arrest in acute type A aortic dissection surgery.

ABSTRACT:

Objectives

Our goal was to investigate whether laboratory signatures on admission could be used to identify risk stratification and different tolerance to hypothermic circulatory arrest in acute type A aortic dissection surgery.

Methods

Patients from 10 Chinese hospitals participating in the Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (5A) study were randomly divided into derivation and validation cohorts at a ratio of 7:3 to develop and validate a simple risk score model using preoperative variables associated with in-hospital mortality using multivariable logistic regression. The performance of the model was assessed using the area under the receiver operating characteristic curve. Subgroup analyses were performed to investigate whether the laboratory s

SUBMITTER: Liu H 

PROVIDER: S-EPMC9645440 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature