Characterization of Blood Outgrowth Endothelial Cells (BOEC) from Porcine Peripheral Blood.

ABSTRACT: The endothelium is a dynamic integrated structure that plays an important role in many physiological functions such as angiogenesis, hemostasis, inflammation, and homeostasis. The endothelium also plays an important role in pathophysiologies such as atherosclerosis, hypertension, and diabetes. Endothelial cells form the inner lining of blood and lymphatic vessels and display heterogeneity in structure and function. Various groups have evaluated the functionality of endothelial cells derived from human peripheral blood with a focus on endothelial progenitor cells derived from hematopoietic stem cells or mature blood outgrowth endothelial cells (or endothelial colony-forming cells). These cells provide an autologous resource for therapeutics and disease modeling. Xenogeneic cells may provide

SUBMITTER: Shradhanjali A 

PROVIDER: S-EPMC9645770 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature