New insights into the comorbid conditions of Turner syndrome: results from a long-term monocentric cohort study.

ABSTRACT:

Purpose

Many questions concerning Turner syndrome (TS) remain unresolved, such as the long-term complications and, therefore, the optimal care setting for adults. The primary aim of this long-term cohort study was to estimate the incidence of comorbid conditions along the life course.

Methods

A total of 160 Italian patients with TS diagnosed from 1967 to 2010 were regularly and structurally monitored from the diagnosis to December 2019 at the University Hospital of Bologna using a structured multidisciplinary monitoring protocol.

Results

The study cohort was followed up for a median of 27 years (IQR 12-42). Autoimmune diseases were the comorbid condition with the highest incidence (61.2%), followed by osteoporosis and hypertension (23.8%), type 2 diabetes (16.2%) and

SUBMITTER: Gambineri A 

PROVIDER: S-EPMC9646560 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature