Associations between urea nitrogen and risk of depression among subjects with and without type 2 diabetes: A nationwide population-based study.

ABSTRACT:

Background

Depression and type 2 diabetes (T2D) are serious public health problems with irreversible health consequences and a significant economic burden on the healthcare system. Previous studies have suggested that blood urea nitrogen (BUN) was inversely longitudinally associated with incidence of diabetes and depression in adults, but few well-designed studies have examined the effects of status of T2D on the full range of relationship between BUN and depression.

Methods

The analysis sample consisted of adults aged≥20 years from the 2007-2014 National Health and Nutrition Examination Survey (NHANES) who completed the Patient Health Questionnaire-9 (PHQ-9), involving 19,005 participants. By stratifying participants according to T2D status, we further assessed the differen

SUBMITTER: Mao Y 

PROVIDER: S-EPMC9646599 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature