Parametric analysis of an efficient boundary condition to control outlet flow rates in large arterial networks.

ABSTRACT: Substantial effort is being invested in the creation of a virtual human-a model which will improve our understanding of human physiology and diseases and assist clinicians in the design of personalised medical treatments. A central challenge of achieving blood flow simulations at full-human scale is the development of an efficient and accurate approach to imposing boundary conditions on many outlets. A previous study proposed an efficient method for implementing the two-element Windkessel model to control the flow rate ratios at outlets. Here we clarify the general role of the resistance and capacitance in this approach and conduct a parametric sweep to examine how to choose their values for complex geometries. We show that the error of the flow rate ratios decreases exponentially as the r

SUBMITTER: Lo SCY 

PROVIDER: S-EPMC9646762 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature