Pilot study in human healthy volunteers on the use of magnetohydrodynamics in needle-free continuous glucose monitoring.

ABSTRACT: The benefits of continuous glucose monitoring (CGM) in diabetes management are extensively documented. Yet, the broader adoption of CGM systems is limited by their cost and invasiveness. Current CGM devices, requiring implantation or the use of hypodermic needles, fail to offer a convenient solution. We have demonstrated that magnetohydrodynamics (MHD) is effective at extracting dermal interstitial fluid (ISF) containing glucose, without the use of needles. Here we present the first study of ISF sampling with MHD for glucose monitoring in humans. We conducted 10 glucose tolerance tests on 5 healthy volunteers and obtained a significant correlation between the concentration of glucose in ISF samples extracted with MHD and capillary blood glucose samples. Upon calibration and time lag remova

SUBMITTER: Hakala TA 

PROVIDER: S-EPMC9646842 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature