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The association between normal serum sodium levels and bone turnover in patients with type 2 diabetes.


ABSTRACT:

Background

Sodium is a critically important component of bones, and hyponatremia has firmly been established as a risk factor associated with the incidence of fragility fractures. However, researches have also revealed that lower serum sodium are linked to reductions in muscle mass and a higher risk of cardiovascular disease even when these levels are within the normal range. Accordingly, this study was developed to examine the relationships between normal serum sodium concentrations and bone turnover in patients with type 2 diabetes (T2D).

Methods

Patients with T2D were enrolled in the present study from January 2021 to April 2022. All patients underwent analyses of serum sodium levels, oral glucose tolerance testing (OGTT), bone turnover markers (BTMs), and dual-energy X-r

SUBMITTER: Huang HY 

PROVIDER: S-EPMC9646934 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature