A case report of primary cardiac angiosarcoma with DNMT3A gene mutation.
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ABSTRACT:
SUBMITTER: Tian K
PROVIDER: S-EPMC9647023 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
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A case report of primary cardiac angiosarcoma with <i>DNMT3A</i> gene mutation.
Tian Kun K Liu Yating Y Zhu Haiying H Wang Tao T Chen Tianxing T Pei Xiaxia X Song Feixue F
Frontiers in oncology 20221027
Cardiac angiosarcoma is a rare disease with a high mortality rate despite its low incidence. Surgery is currently the mainstay treatment strategy for patients with this condition. Herein, we describe a case of primary cardiac angiosarcoma, including symptoms, examination findings, treatment strategy and prognosis. In 2020, the patient was admitted to our hospital, and Next-Generation Sequencing (NGS) revealed a mutation in the <i>DNMT3A</i> gene. Generally, <i>DNMT3A</i> mutations are most commo ...[more]
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