Cardiorespiratory effects of different intraabdominal pressures in sheep: An experimental study.

ABSTRACT: Increased intraabdominal pressure (IAP) during laparoscopy can reduce venous return, but changes in respiratory system mechanics and their effect in left cardiac function are not well documented. This study evaluated the effects of different IAPs on respiratory mechanics and cardiac function in 10 healthy nonpregnant adult Santa Ines ewes randomly submitted to a crossover study using different IAPs: 0 mm Hg (G1), 10 mm Hg (G2), 12 mmHg (G3), and 15 mmHg (G4). Animals were anesthetized and mechanically ventilated (V_T  = 15 ml/kg; positive end-expiratory pressure = 3 cmH₂ O; FiO₂  = 1.0). Pneumoperitoneum was induced by Hasson's trocar cannula. Variables were measured at INITIAL (IAP, 0 mmHg) and FINAL time points for each IAP after 1 h. At FINAL, driving air

SUBMITTER: do Nascimento PRL 

PROVIDER: S-EPMC9647340 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature