The roles of RNA N⁶-methyladenosine in esophageal cancer.

ABSTRACT: Esophageal cancer is a malignant tumour with a high degree of malignancy and high mortality. Its pathogenesis and treatment strategy remain unclear. N⁶-methyladenosine (m⁶A) is important for various biological functions in RNA modification and is currently being investigated extensively. It plays an essential role in RNA modification. m⁶A modification is a dynamic process that reversibly regulates the target RNA through its regulatory factors and plays an important role in several diseases, especially cancer. However, the role of m⁶A in esophageal cancer remains elusive. RNA modification and splicing are regulated by RNA methylation regulators called 'writers' (methyltransferases), 'erasers' (demethylases) and 'readers' (modified RNA-binding prot

SUBMITTER: Teng C 

PROVIDER: S-EPMC9647491 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature