Improving Vancomycin Stewardship in Critically Ill Children.

ABSTRACT:

Background and objectives

Inappropriate vancomycin use is common in children's hospitals. We report a quality improvement (QI) intervention to reduce vancomycin use in our tertiary care PICU.

Methods

We retrospectively quantified the prevalence of infections caused by organisms requiring vancomycin therapy, including methicillin-resistant Staphylococcus aureus (MRSA), among patients with suspected bacterial infections. Guided by these data, we performed 3 QI interventions over a 3-year period, including (1) stakeholder education, (2) generation of a consensus-based guideline for empiric vancomycin use, and (3) implementation of this guideline through clinical decision support. Vancomycin use in days of therapy (DOT) per 1000 patient days was measured by using statistical pro

SUBMITTER: Chiotos K 

PROVIDER: S-EPMC9647566 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature