Orthostatic Hypotension in Parkinson Disease: What Is New?

ABSTRACT:

Purpose of the review

Orthostatic hypotension (OH) is the primary manifestation of cardiovascular autonomic dysfunction in Parkinson disease (PD) and can be a prodromal feature of the disease. We review the recent progress in the field of autonomic dysfunction in PD.

Recent findings

Individuals with isolated neurogenic OH should be followed up frequently because they may evolve into PD, dementia with Lewy bodies, or multiple system atrophy. The prevalence of OH in PD increases with disease stages, but the role of levodopa remains unclear. Measurement of supine and standing heart rate and blood pressure allows for accurate identification of neurogenic OH in the clinic.

Summary

Accurate identification of neurogenic OH in the clinic is crucial for identification of indiv

SUBMITTER: Lamotte G 

PROVIDER: S-EPMC9647798 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature