Variation in aorta attenuation in contrast-enhanced CT and its implications for calcification thresholds.

ABSTRACT:

Background

CT contrast media improves vessel visualization but can also confound calcification measurements. We evaluated variance in aorta attenuation from varied contrast-enhancement scans, and quantified expected plaque detection errors when thresholding for calcification.

Methods

We measured aorta attenuation (AoHU) in central vessel regions from 10K abdominal CT scans and report AoHU relationships to contrast phase (non-contrast, arterial, venous, delayed), demographic variables (age, sex, weight), body location, and scan slice thickness. We also report expected plaque segmentation false-negative errors (plaque pixels misidentified as non-plaque pixels) and false-positive errors (vessel pixels falsely identified as plaque), comparing a uniform thresholding approach and

SUBMITTER: Holcombe SA 

PROVIDER: S-EPMC9648778 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature