Extracellular electrons transferred from honey probiotic Bacillus circulans inhibits inflammatory acne vulgaris.

ABSTRACT: Bacillus circulans (B. circulans) is widely used as an electrogenic bacterium in microbial fuel cell (MFC) technology. This study evaluated whether B. circulans can ferment glucose to generate electricity and mitigate the effects of human skin pathogens. The electricity production of B. circulans was examined by measuring the voltage difference and verified using a ferrozine assay in vitro. To investigate the fermentation effects of B. circulans on inhibition of human skin pathogens, Cutibacterium acnes (C. acnes) was injected intradermally into mice ears to induce an inflammatory response. The results revealed that the glucose-B. circulans co-culture enhanced electricity production and significantly supressed C. acnes growth. The addition of roseoflavin to inhibit flavin production consid

SUBMITTER: Kao HJ 

PROVIDER: S-EPMC9649788 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature