Association between remnant cholesterol and heart failure: A prospective cohort study.

ABSTRACT:

Background

Elevated remnant cholesterol (RC) is associated with a higher risk of various cardiac diseases. Heart failure (HF) usually occurs at the end stage of various cardiac diseases. However, there is limited research on the association between RC and the risk of HF. Therefore, we aimed to provide relevant evidence by determining whether a high RC level also influences the risk of HF.

Materials and methods

In this secondary analysis of the Atherosclerosis Risk in Communities (ARIC) study, we included 12,595 participants without coronary heart disease. We determined the association of the RC level as a continuous or categorical variable with the risk of HF using the multivariable-adjusted Cox proportional hazards models and restricted cubic spline curve.

Results

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SUBMITTER: Liu H 

PROVIDER: S-EPMC9649897 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature