Temporal interference stimulation targeting right frontoparietal areas enhances working memory in healthy individuals

ABSTRACT:

Background

Temporal interference (TI) stimulation is a novel technique that enables the non-invasive modulation of deep brain regions. However, the implementation of this technology in humans has not been well-characterized or examined, including its safety and feasibility.

Objective

We aimed to examine the feasibility, safety, and blinding of using TI on human participants in this pilot study.

Materials and methods

In a randomized, single-blinded, and sham-controlled pilot study, healthy young participants were randomly divided into four groups [TI and transcranial alternating current stimulation (tACS) targeting the right frontoparietal region, TI-sham, and tACS-sham]. Each participant was asked to complete N-back (N = 1 to 3) tasks before, during, and after on

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9650295 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature