Dataset Information

Myocardial infarction following COVID-19 vaccine administration; a systematic review.

ABSTRACT:

Introduction

Covid-19 vaccines have been assessed in randomized trials, which are designed to establish efficacy and safety, but are insufficient in power to detect rare adverse outcomes. Among the adverse cardiac events associated with mRNA COVID-19 vaccines are inflammations (e.g., pericarditis or myocarditis), thrombosis, and ischemia.

Objective

This systematic review aims to evaluate the reported cases of myocardial infarction (MI) after COVID-19 vaccinations.

Method

Web of Science, MEDLINE on OVID, PubMed, and Google Scholar were searched for English-language papers published until March 25, 2022.

Results

This study included 15 papers (10 case reports and 5 case series). In total, 20 individuals were included who had received COVID-19 vaccines and experienced MI. Males (55%) reported more adverse occurrences than females (45%) across the majority of event categories. The mean time from the administration of the vaccine to the onset of symptoms was 2 days (0-10 days). The AstraZeneca vaccine was responsible for more than half of the reported events. In the majority of cases, the event developed after receiving the first dose of vaccination.

Conclusion

MI related to COVID19 vaccination is a rare, but serious and life-threatening condition. Chest discomfort should be regarded as a warning sign, particularly in people who have been administered a dose of the vaccine within the previous two days.

SUBMITTER: Baqi DH

PROVIDER: S-EPMC9650518 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Publications

Myocardial infarction following COVID-19 vaccine administration; a systematic review.

Baqi Dana H DH Kakamad Fahmi H FH Mahmood Zana H ZH Fattah Fattah H FH Ahmed Shaho F SF Hassan Marwan N MN Hama Amin Bnar J BJ Mohammed Shvan H SH Mikael Tomas M TM Hassan Hunar A HA Salh Abdulwahid M AM

Heliyon 20221111 11

<h4>Introduction</h4>Covid-19 vaccines have been assessed in randomized trials, which are designed to establish efficacy and safety, but are insufficient in power to detect rare adverse outcomes. Among the adverse cardiac events associated with mRNA COVID-19 vaccines are inflammations (e.g., pericarditis or myocarditis), thrombosis, and ischemia.<h4>Objective</h4>This systematic review aims to evaluate the reported cases of myocardial infarction (MI) after COVID-19 vaccinations.<h4>Method</h4>We ...[more]

PMID: 36406668

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Dataset Information

Myocardial infarction following COVID-19 vaccine administration; a systematic review.

Introduction

Objective

Method

Results

Conclusion

Publications

Myocardial infarction following COVID-19 vaccine administration; a systematic review.

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