Antioxidative and anti-inflammatory effects of vitamin C on the liver of laying hens under chronic heat stress.

ABSTRACT: In this study, we investigated the therapeutic effect and mechanism of action of vitamin C on chronic heat stress (CHS)-induced liver oxidative damage and inflammation in laying hens. The thermoneutral control group (TN group) was kept at a constant temperature of 22 ± 1°C, while the chronic heat stress group (CHS group) and the vitamin C supplemented group (HSV group) were exposed to heat stress (HS) (36 ± 1°C, 8 h/d). The TN and HS groups were fed the basic diet at will, and the HSV group was supplemented with 300 mg/kg of vitamin C on top of the basic diet. The experimental results showed a significant improvement in body weight and feed intake in the HSV group compared to the HS group. A significantly lower pH and higher HCO3- and PCO₂ levels were observed in the HSV group c

SUBMITTER: Du J 

PROVIDER: S-EPMC9650548 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature