Antidiabetic activity of Solanum torvum fruit extract in streptozotocin-induced diabetic rats.

ABSTRACT:

Background

Solanum torvum Swartz, a medicinal plant belonging to the family Solanaceae, is an important medicinal plant widely distributed throughout the world and used as medicine to treat diabetes, hypertension, tooth decay, and reproductive problems in traditional systems of medicine around the world including Malaysia. The objective of this study was to investigate hypoglycemic, antilipidemic, and hepatoprotective activities, histopathology of the pancreas, and specific glucose regulating gene expression of the ethanolic extract of S. torvum fruit in streptozotocin-induced diabetic Sprague-Dawley rats.

Materials and methods

Acute toxicity study was done according to OECD-423 guidelines. Diabetes was induced by intraperitoneal (i.p.) injection of streptozoto

SUBMITTER: Satyanarayana N 

PROVIDER: S-EPMC9650639 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature