A Comparative Study of Multiparametric MRI Sequences in Measuring Prostate Cancer Index Lesion Volume.

ABSTRACT:

Objectives

To compare the effectiveness of individual multiparametric prostate MRI (mpMRI) sequences-T2W, diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC), and dynamic contrast-enhanced (DCE)-in assessing prostate cancer (PCa) index lesion volume using whole-mount pathology as the ground-truth; to assess the impact of an endorectal coil (ERC) on the measurements.

Materials and methods

We retrospectively enrolled 72 PCa patients who underwent 3T mpMRI with (n = 39) or without (n = 33) an ERC. A pathologist drew the index lesion borders on whole-mount pathology using planimetry (whole-mount_vol). A radiologist drew the borders of the index lesion on each mpMRI sequence-T2W_vol, DWI_vol, ADC_vol, and DCE_vol</

SUBMITTER: Bagcilar O 

PROVIDER: S-EPMC9650977 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature