Evaluating home injection compared with healthcare-setting injection of somatostatin analogs: a systematic literature review.

ABSTRACT:

Purpose

A systematic literature review was conducted to assess the use of home injections (self/partner/healthcare provider [HCP]-administered) of somatostatin analogs (SSAs) as an alternative to healthcare-setting injections in patients with acromegaly and neuroendocrine tumors (NETs).

Methods

MEDLINE/Embase/the Cochrane Library (2001-September 2021), key congresses (2019-2021), and bibliographies of relevant systematic reviews were searched. Eligible studies reported on efficacy/effectiveness, safety, adherence, patient-reported outcomes (PROs), and economic outcomes in populations receiving home injections of SSAs.

Results

Overall, 12 studies were included, all reporting on SSAs (lanreotide Autogel/Depot or octreotide long-acting release) in acromegaly or NETs. Acr

SUBMITTER: Boguszewski CL 

PROVIDER: S-EPMC9651885 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature