Obesity as a risk factor for severe influenza infection in children and adolescents: a systematic review and meta-analysis.

ABSTRACT: Obesity has been recently identified as a predisposing factor for a worse prognosis in viral illnesses such as SARS-CoV-2; however, its role in children with influenza is not yet clarified. The current systematic review and meta-analysis aims to assess whether obesity is a risk factor for either hospitalization or a worse prognosis when hospitalized among children infected by influenza. We systematically searched the following databases using a structured algorithm: MEDLINE, Clinicaltrials.gov, and Cochrane Central Register of Controlled Trials (CENTRAL). Statistical meta-analysis was performed using the "meta" package in R software, and included studies were evaluated using the Newcastle-Ottawa scale. Among children with influenza, obesity increased the odds of hospitalization with a pool

SUBMITTER: Vitoratou DI 

PROVIDER: S-EPMC9652042 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature