Post-Neoadjuvant Treatment Strategies for Patients with Early Breast Cancer.

ABSTRACT: Pre-surgical treatments in patients with early breast cancer allows a direct estimation of treatment efficacy, by comparing the tumor and the treatment. Patients who achieve a pathological complete response at surgery have a better prognosis, with lower risk of disease recurrence and death. Hence, clinical research efforts have been focusing on high-risk patients with residual disease at surgery, who may be "salvaged" through additional treatments administered in the post-neoadjuvant setting. In the present review, we aim to illustrate the development and advantages of the post-neoadjuvant setting, and to discuss the available strategies for patients with early breast cancer, either approved or under investigation. This review was written after literature search on main scientific database

SUBMITTER: Agostinetto E 

PROVIDER: S-EPMC9654353 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature