Complexation of Gold(III) with Pyridoxal 5'-Phosphate-Derived Hydrazones in Aqueous Solution.

ABSTRACT: Today, complexes of gold(I) and gold(III) are recognized as promising drugs for the treatment of bacterial infectious diseases and oncological diseases, respectively. It is of interest to broaden the area of potential use of gold(III) compounds to the pathogenic microorganism as well. The first step towards the development of new antibacterial drugs based on Au³⁺ complexes is the study of their stability in an aqueous solution. The present contribution reports on the investigation of gold(III) complexation with five hydrazones derived from a well-known biologically active compound, pyridoxal 5'-phosphate (one of the aldehyde forms of the B₆ vitamin). The complex formation in aqueous solutions was confirmed by mass spectrometry and fluorescent spectroscopy. The stoichi

SUBMITTER: Kuranova NN 

PROVIDER: S-EPMC9654535 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature