Maternal Pre-Pregnancy Body Mass Index, Gestational Weight Gain and Children's Cognitive Development: A Birth Cohort Study.

ABSTRACT: To investigate the joint effect of maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on children's cognitive development. We recruited 1685 mother-child pairs from the Ma'anshan Birth Cohort in China. Pre-pregnancy BMI and GWG were calculated based on the height and weights measured at multiple antenatal checkups. Children's cognition was assessed by Wechsler Preschool and Primary Scale of Intelligence-Fourth Edition. Poisson regression model was used to analyze the association between maternal pre-pregnancy BMI and children's cognitive dimensions under different GWG categories. Women with overweight or obese before pregnancy were more likely to obtain excessive GWG. When women had excessive GWG, pre-pregnancy overweight was associated with low children's PSI (

SUBMITTER: Hao X 

PROVIDER: S-EPMC9654549 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature