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Postprandial Responses to a Standardised Meal in Hypertension: The Mediatory Role of Visceral Fat Mass.


ABSTRACT: Postprandial insulinaemia, triglyceridaemia and measures of inflammation are thought to be more closely associated with cardiovascular risk than fasting measures. Although hypertension is associated with altered fasting metabolism, it is unknown as to what extent postprandial lipaemic and inflammatory metabolic responses differ between hypertensive and normotensive individuals. Linear models adjusting for age, sex, body mass index (BMI), visceral fat mass (VFM) and multiple testing (false discovery rate), were used to investigate whether hypertensive cases and normotensive controls had different fasting and postprandial (in response to two standardised test meal challenges) lipaemic, glycaemic, insulinaemic, and inflammatory (glycoprotein acetylation (GlycA)) responses in 989 participants

SUBMITTER: Louca P 

PROVIDER: S-EPMC9655022 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature