Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics.

ABSTRACT: Lung cancer is one of the most lethal forms of cancer, with a very high mortality rate. The precise pathophysiology of lung cancer is not well understood, and pertinent information regarding the initiation and progression of lung cancer is currently a crucial area of scientific investigation. Enhanced knowledge about the disease will lead to the development of potent therapeutic interventions. Extracellular vesicles (EVs) are membrane-bound heterogeneous populations of cellular entities that are abundantly produced by all cells in the human body, including the tumor cells. A defined class of EVs called small Extracellular Vesicles (sEVs or exosomes) carries key biomolecules such as RNA, DNA, Proteins and Lipids. Exosomes, therefore, mediate physiological activities and intracellular commun

SUBMITTER: Paramanantham A 

PROVIDER: S-EPMC9655370 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature