Microscopic Hematuria at Kidney Donor Screening and Post-Donation Kidney Outcomes.

ABSTRACT: Although guidelines recommend a kidney biopsy in prospective living kidney donors with unexplained microscopic hematuria, individuals with mild hematuria are commonly allowed to donate without a biopsy. However, the prognostic implications of pre-donation hematuria are unclear. We investigated whether pre-donation microscopic hematuria is associated with changes in post-donation eGFR, proteinuria, or blood pressure. We included 701 living kidney donors with two pre-donation urinalyses and post-donation annual evaluations of the estimated glomerular filtration rate (eGFR), protein/creatinine ratio (PCR), and systolic blood pressure (SBP). The association between pre-donation microscopic hematuria and outcomes was assessed using generalized linear mixed models. The median [interquartile rang

SUBMITTER: van der Weijden J 

PROVIDER: S-EPMC9655639 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature