Determination of Melting Parameters of Cyclodextrins Using Fast Scanning Calorimetry.

ABSTRACT: The first evidence of native cyclodextrins fusion was registered using fast scanning calorimetry (FSC) with heating rates up to 40,000 K s^-1. The endothermal effects, detected at low heating rates, correspond to the decomposition processes. Upon the increase of the heating rate the onset of these effects shifts to higher temperatures, reaching a limiting value at high heating rates. The limiting temperatures were identified as the melting points of α-, β- and γ-cyclodextrins, as the decomposition processes are suppressed at high heating rates. For γ-cyclodextrin the fusion enthalpy was measured. The activation energies of thermal decomposition of cyclodextrins were determined by dependence of the observed thermal effects on heating rates from 4 K min^-1 in conventional

SUBMITTER: Gatiatulin AK 

PROVIDER: S-EPMC9655725 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature