Emergence of psychiatric adverse events during antipsychotic treatment in AP-naive children and adolescents.

ABSTRACT:

Background

Over the last decades, antipsychotic prescriptions in children have increased worldwide. However, adverse events are frequently observed, with some such as psychiatric adverse events remaining poorly documented.

Method

The French ETAPE study is a 12-month naturalistic prospective multisite study that included 190 antipsychotic-naïve pediatric patients (mean age = 12 ± 3 years), treated by antipsychotic for psychotic or non-psychotic symptoms. From the ETAPE database, we performed additional analyses focusing on psychiatric adverse events.

Results

Children received mainly second-generation antipsychotic for conditions out of regulatory approval, with risperidone and aripiprazole being the most frequent (respectively 52.5% and 30.83%). Clinicians reported 244

SUBMITTER: Menard ML 

PROVIDER: S-EPMC9655798 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature