New insights into fibrous cap thickness of vulnerable plaques assessed by optical coherence tomography.

ABSTRACT:

Objective

Vulnerable plaques with fibrous cap thickness (FCT) of ≤65 μm are prone to rupture and/or thrombosis. However, plaques with FCT > 65 μm cause acute myocardial infarction and even sudden death. We aimed to investigate the relationship between 65 < FCT ≤ 80 μm and plaque rupture and/or thrombosis using optical coherence tomography (OCT).

Methods

OCT was performed on culprit lesions in 502 consecutively enrolled patients to identify FCT. Patients were classified into three groups according to FCT: Group A (FCT ≤ 65 μm, n = 147), Group B (65 < FCT ≤ 80 μm, n = 84) and Group C (FCT > 80 μm, n = 271). Clinical and laboratory data was collected from the inpatient medical record system.

Results

Plaques with thinner FCT, especially < 65 μm, were more susceptible to r

SUBMITTER: Liu X 

PROVIDER: S-EPMC9655862 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature