Biomarker Expression of Peri-Implantitis Lesions before and after Treatment: A Systematic Review.

ABSTRACT: The need to predict, diagnose and treat peri-implant diseases has never been greater. We present a systematic review of the literature on the changes in the expression of biomarkers in peri-implant crevicular fluid (PICF) before and after treatment of peri-implantitis. Bacterial composition, clinical and radiographic parameters, and systemic biomarkers before and after treatment are reported as secondary outcomes. A total of 17 studies were included. Treatment groups were non-surgical treatment or surgical treatment, either alone or with adjunctive therapy. Our findings show that non-surgical treatment alone does not influence biomarker levels or clinical outcomes. Both adjunctive photodynamic therapy and local minocycline application resulted in a reduction of interleukin (IL)-1β and IL-1

SUBMITTER: Moaven H 

PROVIDER: S-EPMC9659150 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature