Composite Hydrogel Microspheres Encapsulating Hollow Mesoporous Imprinted Nanoparticles for Selective Capture and Separation of 2'-Deoxyadenosine.

ABSTRACT: Hollow mesoporous silica nanoparticles have been widely applied as a carrier material in the molecular imprinting process because of their excellent properties, with high specific surface area and well-defined active centers. However, these kinds of materials face the inevitable problem that they have low mass transfer efficiency and cannot be conveniently recycled. In order to solve this problem, this work has developed a composite hydrogel microsphere (MMHSG) encapsulated with hollow mesoporous imprinted nanoparticles for the selective extraction of 2'-deoxyadenosine (dA). Subsequently, the hollow mesoporous imprinted polymers using dA as template molecule and synthesized 5-(2-carbomethoxyvinyl)-2'-deoxyuridine (AcrU) as functional monomer were encapsulated in hydrogel. MMHSG displayed g

SUBMITTER: Liu L 

PROVIDER: S-EPMC9659214 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature