Morphology of the murine choroid plexus: Attachment regions and spatial relation to the subarachnoid space.

ABSTRACT: The choroid plexus has recently been identified as a possible migration route for peripheral immune cells into the central nervous system. For future investigation of this route, profound knowledge of the morphology of the murine choroid plexus is a prerequisite. We here present a detailed morphological description of the murine choroid plexus, its attachment regions as well as its spatial relation to the subarachnoid space. We used micro-computed tomography of immersion-contrasted fixated brains to generate three-dimensional models of the ventricle system and the choroid plexus and aligned micro-computed tomography-based sections with histological paraffin-embedded sections after immunohistochemical labeling of the basal lamina and choroid plexus epithelium marker proteins (laminin and aq

SUBMITTER: Greiner T 

PROVIDER: S-EPMC9659632 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature