Computational investigation of the haemodynamics shows criticalities of central venous lines used for chronic haemodialysis in children.

ABSTRACT:

Background

Haemodialysis is a life-saving treatment for children with kidney failure. The majority of children have haemodialysis through central venous lines (CVLs). The use of CVLs in pediatric patients is often associated to complications which can lead to their replacement. The aim of this study is to investigate haemodynamics of pediatric CVLs to highlight the criticalities of different line designs.

Methods

Four models of CVLs for pediatric use were included in this study. The selected devices varied in terms of design and sizes (from 6.5 Fr to 14 Fr). Accurate 3D models of CVLs were reconstructed from high-resolution images including venous and arterial lumens, tips and side holes. Computational fluid dynamics (CFD) analyses were carried out to simulate pediatric work

SUBMITTER: Bruno C 

PROVIDER: S-EPMC9659647 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature