Prevalence of left ventricular hypertrophy in children and young people with primary hypertension: Meta-analysis and meta-regression.

ABSTRACT:

Background

Left ventricular hypertrophy (LVH) is the main marker of HMOD in children and young people (CYP). We aimed to assess the prevalence of LVH and its determinants in CYP with primary hypertension (PH).

Methods

A meta-analysis of prevalence was performed. A literature search of articles reporting LVH in CYP with PH was conducted in Medline, Embase, and Cochrane databases. Studies with a primary focus on CYP (up to 21 years) with PH were included. Meta-regression was used to analyze factors explaining observed heterogeneity.

Results

The search yielded a total of 2,200 articles, 153 of those underwent full-text review, and 47 reports were included. The reports evaluated 51 study cohorts including 5,622 individuals, 73% male subjects, and a mean age of 13.6 years.

SUBMITTER: Sinha MD 

PROVIDER: S-EPMC9659762 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature