Persistent "MRI-negative" lupus myelitis-disease presentation, immunological profile and outcome.

ABSTRACT:

Introduction

Myelitis is the least common neuropsychiatric manifestation in systemic lupus erythematosus (SLE). Magnetic resonance imaging (MRI)-negative myelitis is even rarer. Here, we present the largest cohort of MRI-negative lupus myelitis cases to assess their clinical and immunological profiles and outcome.

Method

A single-center, observational study conducted over a period of 5 years (2017-2021) was undertaken to evaluate patients with MRI-negative lupus myelitis for the epidemiological, clinical, immunological, and radiological features at baseline and followed up at monthly intervals for a year, and the outcomes were documented. Among the 22 patients that presented with MRI-negative myelopathy (clinical features suggestive of myelopathy without signal changes on sp

SUBMITTER: Das S 

PROVIDER: S-EPMC9659815 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature