Bone and mineral metabolism in patients with primary aldosteronism: A systematic review and meta-analysis.

ABSTRACT:

Purpose

Patients with primary aldosteronism (PA) tend to exhibit a high prevalence of osteoporosis (OP) that may vary by whether PA is unilateral or bilateral, and responsive to PA treatment. To explore relationships between bone metabolism, PA subtypes, and treatment outcomes, we performed a systematic review and meta-analysis.

Methods

The PubMed, Embase, and Cochrane databases were searched for clinical studies related to PA and bone metabolism markers. Articles that met the criteria were screened and included in the systematic review; the data were extracted after evaluating their quality. R software (ver. 2022-02-16, Intel Mac OS X 11.6.4) was used for the meta-analysis.

Results

A total of 28 articles were subjected to systematic review, of which 18 were included

SUBMITTER: Wang A 

PROVIDER: S-EPMC9659816 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature